hormonalhair

Saw Palmetto

Saw palmetto supplements are promoted for prostate urinary symptoms and male-pattern hair loss. NCCIH says they are probably not helpful for prostate symptoms, and the evidence for hair loss is too limited to draw conclusions.

Saw palmetto is a small palm tree native to the southeastern United States and West Indies, whose berries are used in dietary supplements. It is most widely promoted for urinary symptoms associated with benign prostatic hyperplasia (BPH) and for male-pattern hair loss. NCCIH says we know enough to conclude that saw palmetto is probably not helpful for urinary symptoms from an enlarged prostate, and that the evidence for hair loss is too limited to draw conclusions. MSK notes adverse effects are generally mild and similar to placebo.

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Research & evidence

Strong support Some support Weak or no supportColours show how well the sources back each point. The reason is next to each one.

NCCIH says we know enough to conclude that saw palmetto is probably not helpful for urinary symptoms associated with an enlarged prostate gland.

Not supported by current evidenceWeak or no support. Trials found no clear benefit

Study details

NCCIH: "We know enough to conclude that saw palmetto is probably not helpful for this purpose." NCCIH: "Saw palmetto is promoted as a dietary supplement for urinary symptoms associated with an enlarged prostate gland ..."

A few small studies have tested saw palmetto, used orally or topically (applied to the scalp), for male-pattern hair loss. The evidence is too limited to allow conclusions to be reached.

Limited evidenceSome support. Based on one or a few small trials

Study details

NCCIH: "A few small studies have tested saw palmetto, used orally or topically (applied to the scalp), for male-pattern hair loss." NCCIH: "The evidence is too limited to allow conclusions to be reached."

There is not enough evidence to determine whether saw palmetto is useful for other health purposes. More studies are needed before definitive conclusions can be made.

Limited evidenceSome support. Reviewers rated the certainty low

Study details

NCCIH: "There is not enough evidence to determine whether saw palmetto is useful for other health purposes." NCCIH: "More studies are needed before definitive conclusions can be made."

Dosage

FormAmount
Any formWhole berries are not standardised and are not the form studied. Use only liposterolic (lipid/sterol) standardised extracts.
Capsule320 mg/day of standardised liposterolic extract (lipid/sterol fraction), commonly as a single dose or split into two 160 mg doses.
Dosage varies by body weight, age, sex, existing health conditions, current medications, and pregnancy/breastfeeding status. The amounts above reflect commonly studied amounts, not a personal prescription. Saw palmetto may increase bleeding risk — stop 2 weeks before surgery. Consult a healthcare provider before use if you take blood thinners.

Side effects

Saw palmetto is generally well tolerated. Side effects are mild and infrequent and may include digestive discomfort, dizziness, and headache. It may increase bruising and bleeding risk. Avoid during pregnancy or breastfeeding.

Well documented Reported (case reports, anecdotal or one study) None reportedThe circle shows how well documented an effect is, not how serious it is. A rarely reported effect can still be serious, so always read ‘When to stop’.

EffectFrequencyWhen to stop
Digestive symptomsWell documentedListed plainly by NIH, MSK or LiverToxMild and infrequentStop and talk to a doctor if you notice any unexpected or concerning symptoms.
DizzinessWell documentedListed plainly by NIH, MSK or LiverToxMild and infrequentStop and talk to a doctor if you notice any unexpected or concerning symptoms.
HeadacheWell documentedListed plainly by NIH, MSK or LiverToxMild and infrequentStop and talk to a doctor if you notice any unexpected or concerning symptoms.

Safety & interactions

Safety

NCCIH says saw palmetto is well tolerated and has been used safely in research studies for up to 3 years. It says adverse effects are mild and infrequent, and may include digestive symptoms, dizziness, and headache. MSK says most effects are reported as mild and similar to effects with placebo, and that saw palmetto may increase the risk of bruising and bleeding. NCCIH says that if you take any type of medicine, talk with your health care provider before using any herbal product, because some herbs and medicines interact in harmful ways.

Contraindications

NCCIH says saw palmetto may be unsafe for use during pregnancy or while breastfeeding. See Drug interactions for medicines to ask about.

Drug interactions

Anticoagulants (blood thinners)Theoretical

MSK says saw palmetto may have additive anticoagulant effects, according to case reports.

Drugs broken down by UGT enzymes (UGT substrates)Theoretical

MSK says saw palmetto inhibits UGT enzymes in vitro and can increase the side effects of drugs metabolized by them.

Established: stated plainly by an authoritative source. Documented: supported by case reports or trial data. Theoretical: based on mechanism, animal data, or a cautious listing. Always check with your pharmacist or prescriber.

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